Croscarmellose Sodium CAS 74811-65-7 Pharmaceutical Excipients
Croscarmellose Sodium is the refined cotton to react with sodium hydroxide to produce the alkali cellulose, and then car
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Basic Info
Model NO. | 74811-65-7 |
Transport Package | Bag |
Specification | 25kg |
Trademark | yanxi |
Origin | China |
HS Code | 29211190 |
Production Capacity | 10000 Tons/Year |
Product Description
Croscarmellose Sodium is the refined cotton to react with sodium hydroxide to produce the alkali cellulose, and then carboxymethylated by chloroacetic acid to get an ionic water-soluble polymer powder, an anionic cellulose ether.
Product Name: Croscarmellose Sodium
Appearance: white or milky white powder
CAS No.: 74811-65-7
Packing: 25kg in drum
Storage: Sealed container in dry place.
Shelf Life:2 years
Croscarmellose sodium resolves formulators′ concerns over long-term functional stability, reduced effectiveness at high tablet hardness levels, and similar problems associated with other products developed to enhance drug dissolution. Croscarmellose sodium is a very commonly used pharmaceutical additive approved by the U.S. Food and Drug Administration. Its purpose in most tablets - including dietary supplements - is to assist the tablet in disintegrating in the gastrointestinal tract promptly. If a tablet disintegrating agent is not included, the tablet could disintegrate too slowly, in the wrong part of the intestine or not at all, thereby reducing the efficacy and bioavailability of the active ingredients.
Item | Index (USP) | Index (CP) |
PH | 5.0-7.0 | 5.0-7.0 |
Loss on drying(%) | ≤10.0 | ≤10.0 |
Na-chloride&Na-glycolate(%) | ≤0.50 | ≤0.50 |
residue on ignition(%) | 14.0-28.0 | 14.0-28.0 |
Heavy metals(ppm) | ≤10.0 | ≤10.0 |
Degree of Substitution | 0.60-0.85 | 0.60-0.85 |
Content of Water-soluble Material(%) | ≤10.0 | ≤10.0 |
Setting Volume(ml) | 10.0-30.0 | 10.0-30.0 |
Retained 200 mesh (74microns) | ≤10.0 |
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