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Oct 15, 2024

10 best probiotics for men 2024, expert reviewed | Fortune Recommends

By Pete Nastasi, CPT, CSNC Expert Verified by Dr. Rob Wildman, PhD, RD, LD, CISSN, FISSN Expert Verified by Victoria Burgess, Phd, CSCS, CISSN Reviewed by Lily Moe Fact Checked by Kelly Uhler Our team

By Pete Nastasi, CPT, CSNC

Expert Verified by Dr. Rob Wildman, PhD, RD, LD, CISSN, FISSN

Expert Verified by Victoria Burgess, Phd, CSCS, CISSN

Reviewed by Lily Moe

Fact Checked by Kelly Uhler

Our team of expert testers analyzed each probiotic in this review for efficacy and safety, noting the potential benefits and any side effects that can occur. Our top priority is ensuring the products we recommend are of the highest quality and offer excellent value to readers.

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We consulted two PhDs in nutrition to find out what probiotics can do for men and which products provide the best value without sacrificing quality. An expert fact-checker reviewed our work for accuracy.

If you’re new to the world of supplements, probiotic supplements may be even more of a mystery. When talking to clients, I often break probiotics down like this: they’re beneficial microorganisms (primarily bacteria) that live inside our gut, aiding in the digestion and absorption of the food we eat. Trillions of these organisms collectively form our gut microbiome, which plays a key role in our digestive health, immunity,and even mental well-being. ( 1 )

The balance and types of probiotics in our bodies can be affected by various factors: diet, medication use, illness, and stress. This is why many men turn to probiotic-rich foods or supplements to boost the number of beneficial bacteria in their gut and support their overall health.

With the wide range of probiotic supplements on the market, finding the right one to meet your specific health needs can be challenging. To help you navigate this, our team reviewed dozens of options, focusing on efficacy, safety, and value. We narrowed it down to a list of the 10 best probiotics for men.

Ritual Synbiotic+ earns our editor’s choice thanks to its comprehensive blend of two clinically-proven probiotic strains, prebiotics, and postbiotics, delivered in a delayed-release capsule. This supplement stands out for its traceable ingredients and effectiveness in promoting gut health and overall well-being. You can read our full review of Ritual Synbiotic+ below.

Medical disclaimer: This article is intended for educational and informational purposes only. It is not intended as a substitute for medical advice. For health advice, contact a licensed healthcare provider.

Ritual’s Synbiotic+ combines prebiotics, probiotics, and postbiotics in a single, shelf-stable capsule to support comprehensive gut health.

There is an increasing amount of evidence suggesting that the gut microbiota undergoes a significant shift in diversity as we age. ( 2 ) Adding a supplement, such as Ritual Synbiotic+, may be beneficial to help counteract these age-related changes.

Synbiotic+ stands out as a probiotic choice for men over 60 because of its comprehensive and science-backed formula. The combination of a prebiotic, probiotic, and postbiotic in one capsule ensures a complete and holistic approach to gut health.

The clinically-studied strains of probiotics chosen for Synbiotic+, including Lactobacillus rhamnosus and Bifidobacterium animalis , are specifically beneficial for digestive health, immune function, and inflammation reduction, all crucial for older adults. ( 3 ) The delayed-release capsules are designed to withstand stomach acid, ensuring that the probiotics are able to reach the gut effectively.

Furthermore, Ritual’s commitment to clean and transparent ingredients, avoiding allergens and unnecessary additives, further enhances its suitability for men over 60 who are focused on maintaining overall health.

Although I’m not over 60, I have used this probiotic supplement in the past. The once-daily capsule is slightly larger than average, but still easy to swallow. Additionally, I was pleasantly surprised by its minty taste, which made the experience of using the product a little more enjoyable.

One thing to note is that Ritual’s products are purchased as part of a subscription plan costing $54 per bottle. After your initial order, you will automatically be enrolled in their subscription service which will send you a new bottle of Synbiotic every 30 days. While some consumers enjoy this subscription based model, ensuring a constant supply of probiotics without interruption, others may prefer to cancel their subscription directly after purchase.

Ritual’s Synbiotic+ has received many positive reviews on Amazon, with customers commenting on the robustness of the formula which includes a pre, post, and probiotic.

“I have tried countless pre/post/pro biotics over the years and this is hands down the best and most effective. It is a little pricey but well worth it.”

Kat Z., Amazon

Amazon customer Elizabeth M. loves that Synbiotic+ is a three-in-one.

“All of the previous probiotics I’ve used never worked for me. I have a bad gut but after taking these for a month, I feel better all around and have been able to eat foods that I haven’t before without crazy bloating. I already ordered a second bottle and will continue to use this product. Also I’ve been able to take this on an empty stomach with no problem or sick feelings! And the fact that I only have to take one a day is so easy plus the minty flavor is a game changer!!”

While I enjoyed the mint flavor, some consumers appear to disagree. Fortunately, since this supplement is just a single pill, it can be taken quickly, making it manageable even if the taste isn’t to your liking.

“Something about the mint taste makes this hard to swallow. Typically mint things aren’t “food” to swallow like gum or toothpaste so it’s very unintuitive. Other than that the packaging is nice, nice branding, I keep them in the fridge. I take them on an empty stomach and these don’t send me to the toilet as quick as other brands, not that that makes any difference,” writes Rochelle.

VSL#3 Capsules are a probiotic medical food, not a dietary supplement, specifically formulated to provide nutrition support for gastrointestinal conditions like irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) like ulcerative colitis. ( 4 )

VSL#3 Capsules are a probiotic medical food scientifically formulated to provide nutrition support for serious gut issues including IBS and ulcerative colitis. A 2020 review article published in World Journal of Clinical Cases points out that VSL#3 may alleviate IBS symptoms like diarrhea and abdominal pain, as well as well as reduce flare-ups in people with ulcerative colitis. ( 4 )

The strains of probiotics in VSL#3 may support gastrointestinal health by improving the strength of the intestinal lining and helping to balance the gut’s microbiome. ( 4 ) Early research also suggests that the unique probiotic formula may support general health and protect against chronic diseases like obesity, liver disease, and Type 2 diabetes. ( 4 ) But, more research is needed to better understand how VSL#3 Capsules may benefit healthy people.

VSL#3 is a probiotic medical food, not a dietary supplement. The FDA classifies medical foods as a food specifically formulated and taken under the supervision of a physician for the dietary management of a disease or condition. ( 5 ) You should only use VSL#3 when recommended by your doctor as a form of nutrition support for your gastrointestinal condition.

Further, dosing for VSL#3 isn’t clear and two capsules have 112.5 billion CFUs,the highest dose of probiotics on our list. Instructions say to take two capsules as needed—up to four times a day. At the maximum dose, you may get 450 billion CFUs. Though there are no set guidelines for probiotic dosing, most contain between 1 and 50 CFUs. ( 6 ) Getting a dose that’s too high may cause side effects like abdominal pain or diarrhea. Your doctor can provide guidance on dosing and monitor for side effects and adjust as needed.

It’s worth pointing out that VSL #3 Capsules do need to be refrigerated, so if you’re looking for an on-the-go option, you may need to try something else.

At $2.20 per serving, VSL #3 Capsules cost more than the average market price for probiotics. You can save 10% with a monthly subscription and VSL#3 is health savings account (HSA) and flexible spending account (FSA) eligible and you may be able to save an additional 30-40% if HSA/FSA approved.

If you are experiencing IBS and are looking for a probiotic, check out our best probiotics for IBS .

Most of the more than 2,400 reviews for VSL#3 on Amazon are positive. Customers find the probiotic medical food effective, but don’t like the price. A few Amazon reviewers also expressed concern about getting their shipment without a cold pack.

“Have used this product for over a month, and it seems to be helping my digestive system.”

LWoods, Amazon

Another verified Amazon buyer, Dusty R., writes, “The purpose of VSL#3 is worthwhile but the cost is outrageous.”

Clair T., on the other hand, expressed concerns about shipping saying, “This item is supposed to arrive cold… mine was warm.”

Transparent Labs Gut Health boasts an impressive 100 billion CFU count, featuring 10 unique strains of probiotics specifically formulated to support digestive health.

Transparent Labs Gut Health is our pick for the most comprehensive probiotic for several reasons. The supplement contains a diverse range of probiotics, including well-studied strains like Lactobacillus acidophilus and Lactobacillus rhamnosus . Strains like these play crucial roles in human health, aiding in digestion, food absorption, waste metabolism, and the production of amino acids and short-chain fatty acids. ( 7 )

These strains have been shown to be resistant to stomach acid and bile salts, increasing their chance of surviving digestion and reaching the intestines while still viable. ( 8 ) This is actually an important feature because the digestive tract is designed to eliminate harmful pathogens that we may encounter through the food we eat and drink. While this protective mechanism is effective at killing potentially harmful bacteria, it can also destroy beneficial probiotic bacteria. Therefore, strains that are resistant to stomach acid are particularly advantageous for promoting gut health.

The broad spectrum of beneficial bacteria in this product can significantly support overall gut health, working to improve digestion and reduce gastrointestinal issues. ( 9 ) Furthermore, this supplement boasts the highest CFU count on our list, offering an impressive 100 billion CFU per serving. CFU stands for colony forming units; they’re a measure of the number of living microorganisms in a probiotic supplement. ( 10 ) Ultimately, a supplement’s CFU count is an indicator of its potency and potential effectiveness.

Our product tester used this probiotic for several days, which wasn’t long enough to notice any significant positive health effects. However, he noted a few insights into the supplement’s form and ease of use. The capsules are approximately the length of a quarter, and our tester found them “easy to knock down.” He also appreciated that there was no aftertaste, making the supplement easy to take regularly.

Nutricost Probiotic Complex offers exceptional value as a budget-friendly supplement, providing 60 servings per container. This product also has a potent CFU count of over 50 billion probiotics per serving, which helps to ensure its effectiveness in supporting digestive health.

Nutricost is known for providing high-quality supplements at affordable prices. A prime example of this is their Probiotic Complex, which offers an impressive 60 servings for under $20, making it the most cost-effective option on our list.

Despite its budget-friendly price tag, this supplement doesn’t compromise on quality. With 10 strains of beneficial bacteria and a CFU count that exceeds 50 billion per serving, Nutricost delivers a concentrated and broad-spectrum probiotic. Furthermore, Nutricost maintains rigorous quality standards in their supplement manufacturing process. This probiotic is produced in a regulated GMP facility, is third-party tested, and is free from GMOs and gluten.

It’s important to note Nutricost’s recommendation to refrigerate the product for maximum potency. Nevertheless, our testing revealed standard shipping practices, exposing the supplement to non-refrigerated conditions. It is possible that through this process, it may lose some potency between the time it leaves the manufacturer and when it reaches your door.

Despite these potential shipping issues, we still feel that this product provides excellent value. Whether you’re on a tight budget or simply looking for a reliable probiotic supplement without the unnecessary frills, then Nutricost Probiotic Complex may be worth trying for yourself.

A majority of online reviews for Nutricost Probiotic Complex are positive. Customers seem to find it helpful in addition to affordable.

“Great to find a probiotic at such a great price! Don’t forget to refrigerate.”

Barry W., Amazon

While there are a few less favorable reviews, they are mainly in reference to whether they noticed any immediate benefits.

“I’ve used other brands that have an immediate improvement on my digestive process,” says Eric P. “This brand just doesn’t do that.”

It’s important to recognize that not everyone will experience rapid improvements from using a probiotic. It’s common for these supplements to take a few weeks or even longer before any noticeable results are apparent.

Ora Trust Your Gut contains six strains of probiotics, including Lactobacillus acidophilus DDS-1 to support digestion, and prebiotics to help feed good gut bacteria.

Ora Organic Trust Your Gut Daily Essential Probiotic + Prebiotic is our pick for the best prebiotic and probiotic for several reasons. The supplement contains six well-studied, numbered strains of probiotics, including Lactobacillus acidophilus DDS-1 and Lactobacillus reuteri UALre-16. These strains help promote wellbeing by aiding in digestion, improving inflammation, and helping reduce symptoms of lactose intolerance. ( 7 , 11 ) Additionally, research shows these strains are resistant to stomach acid, which helps increase the likelihood the probiotics reach the intestines while still viable. ( 7 )

The product also contains prebiotics, which serve as nourishment for the probiotic bacteria, to help to ensure the beneficial microbes can flourish. Ora Organic uses prebiotics in the form of Organic Jerusalem Artichoke Inuli. Jerusalem artichokes are high in inulin, which is a dietary fiber that can help regulate bowel movements. ( 12 )

We also like that this prebiotic and probiotic is dairy-free, making it vegan friendly. Often, prebiotics are found in dairy products, so this product can benefit those who may otherwise have issues getting enough prebiotics and probiotics in their diets. Ora recommends taking two Trust Your Gut capsules daily with food. If capsules aren’t for you, the brand recommends breaking them open and mixing into a smoothie.

At $1.33 per serving, this product’s price falls squarely in the middle of our list. We like that it has both pre and probiotics and is also vegan- and vegetarian-friendly, making this a good option for those looking to add more gut health support to their diets who may otherwise be unable to consume traditional forms of probiotics.

Over 2,700 reviewers on Amazon rate this product an average of 4.3 out of 5. Customers report that this supplement has helped them feel less bloated and have more regular bowel movements. Users like that this is a plant-based supplement. Some customers note there is an adjustment time for taking the supplement where they felt worse before feeling better.

“I have struggled with GI issues for years. Other probiotics didn’t do anything or contained dairy and made my food sensitivity issues worse. After taking these vegan probiotics for a short time, I noticed improvement. Less boating and more regular. I take one a day rather than the two per day suggested. 10/10 life improving.”

Ashley M., Amazon

Some reviewers wish the supplement cost a bit less, and others reported the product either didn’t work for them or exacerbated certain GI symptoms.

“I’ve never experienced such bad cramping, headaches, and sickness from a probiotic before. I had to stop taking after still halving the dose. It did not work well with my system at all. Even worse, I am unable to get a refund,” says verified Amazon customer Victoria.

Onnit Total Gut Health contains a blend of digestive enzymes, prebiotics, probiotics, and betaine HCl, which has been shown to improve intestinal health. ( 13 )

Multi-strain probiotic supplements, such as Onnit Total Gut Health, have been shown to have the potential to improve IBS symptoms when used over an extended period of time. This is because they can help slow down the time of digestion, allowing the body to process nutrients and lessen bowel movements. ( 14 ) Onnit’s formula incorporates both probiotics and prebiotics , in addition to digestive enzymes.

The probiotic bacteria, which includes five different strains and the probiotic yeast Saccharomyces boulardii can help to restore the balance of gut microbiota, which is often disrupted in IBS patients. Some of the probiotics in Onnit also have potential anti-inflammatory properties that can help reduce low-grade inflammation in the gut, which is believed to be a major contributing factor to IBS symptoms. ( 14 ) Prebiotics are sugars that provide essential nutrition to probiotics in the gut, allowing them to grow effectively and potentially enhancing their effectiveness. ( 15 )

Moreover, digestive enzymes aid in breaking down food, potentially alleviating symptoms such as bloating and gas, which are common concerns for individuals with IBS. ( 16 ) This multi-faceted approach addresses various aspects of IBS, leading to potential improvements in individuals dealing with this condition.

Backed by Onnit’s reputation for quality assurance and positive reviews from users with IBS, Onnit Total Gut Health emerges as a reliable choice. However, it’s essential for individuals to consult a healthcare professional before starting any new supplement regimen, especially when trying to manage IBS. This personalized guidance helps to ensure that a chosen solution, such as probiotic supplementation, aligns with individual health needs and medical history.

Our product tester for Onnit Total Gut Health, a certified personal trainer, used this probiotic for several days. They noted the supplement was more or less odorless and tasteless, making it easy to take on a daily basis. They also noted a solution to the seven capsule dose: dividing it into smaller portions, which made the full serving easier to swallow compared to taking them all at once.

Many Amazon customers enjoy Onnit Total Gut Health, noting how the supplement helped settle their stomach.

“I suffer from non-alcoholic fatty liver disease as well as IBS. The digestive enzymes in this really help break my food down and feel less bloated. The mix of pre- and probiotics have done a great job of settling my stomach as well. Between the two of them mixed in this packet, I have found a lot of relief from my issues. Granted, the issues are not gone, but they are now well within the manageable range. I love this stuff!”

Malice F., Amazon

Amazon customer Veronica comments that while she wasn’t originally sold on the idea of taking Onnit every day for her IBS, she quickly changed her tune after trying out the supplement.

“In 20 mins my pain was gone and felt 90% better! I still wasn’t sold but I thought I will keep taking them and what a world of difference I feel today taking them daily,” she writes. “I just thought my pains were normal and dealt with the issues I have and after taking these I no longer have the issues I had for years! I recommend these to anyone with IBS, who is lactose intolerant, suffers from gas, ect.”

However, while consumers seem to enjoy the product, it’s hard not to note the cost of this supplement. If you have the budget, then this may be an effective option for supporting your digestive health.

“Love these pills…they’ve helped my stomach so much with bloating. Wish they were cheaper tho…pretty pricey,” Amazon customer Maha, S. writes.

Sunergetic Prebiotic Gummies offer a convenient and tasty way to support your gut health.

Sunergetic Probiotic Gummies helps users easily incorporate probiotics into their daily routine, ensuring they can support their gut health without the hassle of traditional supplement forms. And, the form isn’t the only thing we like about this supplement—the formula holds up as well.

The inclusion of the Bacillus subtilis strain in this supplement, which is known for its well-documented benefits, further enhances the appeal of these gummies. This strain is a well-tolerated, safe, and effective way to alleviate gas-related symptoms in healthy adults. ( 17 ) The clinically recommended dose is at least 2 billion CFUs per day and Sunergetic provides 5 billion CFUs, which exceeds this recommendation. ( 17 ) Having a higher CFU count can be beneficial because it increases the likelihood of the probiotics colonizing the gut effectively and exerting their beneficial effects.

This also positions Sunergetic Probiotic Gummies as a potential alternative to common over-the-counter medications formulated to reduce bloating and gas, which often come with a range of potential negative side effects. If you’re interested in other probiotic gummies, we suggest checking out Olly. They offer one of the best multivitamins for teens , and also have numerous probiotic supplements, including their combination probiotic + prebiotic supplement.

Many customers rave about Sunergetic’s taste—this is to be expected, considering its gummy form. But, with flavored supplements, it’s always beneficial to check out consumer reviews to see how others enjoy the taste and sweetness level.

“Besides being organic, these taste great. They work for me, high dose of 5 billion CFU per two gummies. I have been taking one daily and will graduate onto taking two daily as recommended. Highly recommend this to everyone!”

Anne B., Amazon

Some customers didn’t notice any difference in their digestive health.

“I expected a change in my digestive system; there wasn’t any,” writes Amazon customer Sarah F., “Especially compared to other probiotics I have taken. But because they were organic, I thought I would give them a try.”

Legion Biome is an all-natural, science-backed probiotic with multiple strains of probiotic bacteria. Legion claims the specific bacteria were selected to help improve digestion, immunity, and support healthy metabolism.

Legion has committed to never using artificial ingredients in their dietary supplements, including their Legion Biome. This product is a combination probiotic and prebiotic supplement that’s formulated to improve digestive health, immunity, and metabolism.

The three probiotics in Legion Biome include Bacillus subtilis , Bifidobacterium lactis , and Lactobacillus plantarum . Each of these strains were selected for their unique properties, ensuring a holistic approach to gut health.

Bacillus subtilis is known for its resilience and ability to survive harsh conditions, such as stomach acid, making the probability of it reaching the gut more likely. It is also believed to support digestive health by promoting a healthy balance of beneficial bacteria in the gut, potentially enhancing immune function, and contributing to overall well-being. ( 18 )

Bifidobacterium lactis is a species of bacteria that naturally resides in the human gastrointestinal tract and is considered one of the beneficial or “friendly” bacteria that plays a vital role in maintaining gut health. Known for its ability to break down lactose, the sugar found in milk and dairy products, it can be very beneficial for individuals who suffer from lactose intolerance. It may also help regulate bowel movements, support immune function, and alleviate symptoms of digestive discomfort, such as bloating and gas. ( 19 )

Lactobacillus plantarum is commonly found in fermented foods like sauerkraut, kimchi, and pickles, as well as in the human gut. This particular species is believed to promote digestive health by producing lactic acid and other compounds that may help maintain a healthy pH balance in the gut. Additionally, L. plantarum appears to play a role in the maintenance of a healthy gut microbiota, a factor that has been linked to reductions in weight and body mass index in overweight individuals. ( 20 )

We also love that Legion Biome is third-party tested for heavy metals, microbes, allergens, and other contaminants to ensure it meets FDA purity standards.

Our product tester for Legion Biome reported that the capsules have no real taste and are easy to swallow; she was able to take the full serving size of two capsules at the same time. She also noted that the instructions on the label were specific and recommended taking the probiotic first thing in the morning with a meal.

If you’re looking to promote digestive health and manage your weight, check out our best probiotic supplements for weight loss .

Amazon customers are largely pleased with Legion’s gut-forward formula.

“ I switched to the Legion Biome probiotic from another supplement brand as the other brand that I was taking was not as accessible and I was concerned that my body would not be compatible with this probiotic, but I was definitely proven wrong. I have had no gut/GI/tummy troubles with this supplement. They are easy to swallow, tasteless, and do not impact my regularity in a negative way. I love the Legion transparency and will definitely continue to make these a part of my supplement routine!”

Courtney A., Amazon

Another reviewer from Amazon, whose username is “Smiling Mona,” unfortunately had a negative experience.

“I took this for a few weeks but it gave me so much bloating and gas I had to stop,” they wrote. “For the dollar price and how I can’t return it’s not worth it. I was only taking half a dose and it still gave me stomach cramps. Thank God I work from home.”

Negative side effects such as bloating and gas are fairly common when adding or switching to a new probiotic. In most cases, these issues resolve themselves within a few weeks once your body gets used to the new bacteria.

Sports Research Daily Probiotics is a daily capsule that contains 60 billion CFUs from 12 different probiotic strains, making it the second strongest probiotic on our list.

Many probiotic supplements are gluten-free, but not all take the same precautions that Sports Research does to confirm no cross-contamination takes place. The company manufactures all supplements in a cGMP compliant facility. In addition, Sports Research Daily Probiotics is third-party tested, which is another safeguard against gluten and other potential contaminants like heavy metals, allergens, and microbes.

One of the standout features of this supplement is the delayed release veggie capsule, which helps the 12 strains of beneficial bacteria reach the intestines alive and intact. The innovative capsule technology helps protect the probiotic bacteria from the highly acidic environment of the stomach. Then, once the delayed-release capsule reaches the intestines, it dissolves and releases the probiotics where they can colonize and exert their beneficial effects. This has the potential to enhance the overall effectiveness of the supplement, maximizing its potential benefits for digestive health.

The supplement is also well-dosed, providing 60 billion CFUs per serving. This makes it the second most concentrated product on our list. It’s also shelf-stable, eliminating the need for refrigeration and making it convenient for travel or on-the-go use.

For the best results, Sports Research recommends taking one capsule daily with food. This is another probiotic supplement I’ve used in the past and I still had a few at the house. The capsule measures around ¾ of an inch in length, is easy to swallow, and has no discernable smell or taste.

At $0.93 per serving, you really can’t beat the value that this product offers. Sports Research is the second most concentrated probiotic supplement on our list providing 60 billion CFUs while maintaining its affordable price point.

Many Amazon users attest to experiencing noticeable benefits within the first week of adding Sports Research’s probiotic to their regular routine.

“Honestly I’ve only taken it for maybe 4 days now and I’ve already seen improvements in my gut health and digestive system as digestive issues run in my mother’s side of the family and I just started developing those dear issues lol. I would highly recommend this product to anyone suffering with stomach issues and problems ‘going.’”

Amanda, Amazon

Quentin L., another Amazon customer, noticed his bloating lessened after taking this supplement.

“I just purchased this product recently and have only been using it for one week however I do notice a difference when I am taking the product and I don’t have the normal stomach bloat or extreme feeling of fullness once I take this product,” he writes. “It does work well with some other vitamins and minerals that I’m taking and it is very easy to use as it does not have to be refrigerated like some other products that I have used in the past!”

While the majority of reviews for this product are very positive, there are a handful of consumers who had a negative experience, specifically stomach issues after using the supplement.

“Well.. I wanted to like this product, as the company seems to be a good one… But, day after day stomach problems would creep up after about 1/2 hour after taking this… In the morning or at night, with food or without, stomach issues… I think it’s gotta be the capsule, as another one of their supplements did the same thing… So… I would not recommend this at all… There are other options out there, so you might want to try them instead,” writes Amazon customer RJ.

It’s worth noting that this user updated their review saying she was offered a refund by the company and that they had, “very nice customer service.” It’s encouraging to see that Sports Research reached out to make sure the customer was happy.

Biotics 8 offers a well-rounded supplement that includes a blend of probiotics, prebiotics, digestive enzymes, and vitamin D.

There are 10 different strains of probiotics in the Biotics 8 formula. In addition, this product also contains two prebiotics, inulin from chicory and fructooligosaccharides, three digestive enzymes, amylase, lipase, and protease, and vitamin D. The prebiotics feed the Biotics 8 probiotic formula and the enzymes aid in the absorption of nutrients.

Based on the ingredients in this supplement, this product is formulated to benefit men over 50. The 20 billion CFUs of probiotics may help support gut health and the digestive enzymes may aid in digestion, potentially reducing the negative side effects like bloating and gas that are commonly experienced when adding a new probiotic to your diet. ( 22 ) Additionally, the prebiotics included in this formula can help the probiotics thrive in the gut, enhancing their overall effectiveness. ( 15 )

Research suggests that probiotics may also help improve cognitive function and overall mood in older adults. This is especially relevant because the diversity of the gut microbiota tends to change with age. ( 2 ) Studies have shown a relationship between probiotics and improvements in the gut-brain axis, which promotes both cognitive and mental health in aging adults. ( 21 ) Although these benefits are promising, further research is necessary to fully substantiate these effects.

There’s no denying that this supplement comes with a premium price tag. However, you can significantly reduce the cost by opting for their five pack bundle, which includes a buy three get two free offer. This deal brings the price down to $1.30 per serving, making it comparable to other probiotics on our list.

Despite the savings, this bundle requires a considerable upfront investment, especially if you’re uncertain about the product’s effectiveness for your needs. While the company does provide a 60-day money-back guarantee, it’s essential to carefully read the fine print on their website to fully understand the terms and ensure you can take advantage of this offer if the product doesn’t meet your expectations.

Every probiotic for men we review is rated across six primary categories. Each category is assigned a different percentage weight of the total score based on its relative importance when considering whether or not you should purchase a probiotic for men. Probiotics for men can also earn bonus credits that boost the overall rating for third-party testing credentials from NSF, Labdoor, and more.

You can check out our complete probiotic testing methodology here .

There are many different probiotic strains, each designed to address a specific men’s health goal. Avoiding proprietary blends is crucial for transparency, allowing consumers to know exactly what and how much of each ingredient is included, ensuring a better assessment of the product’s effectiveness and safety.

Identifies the specific strains of probiotics or beneficial bacteria present in the product and how the strains support men’s health. The importance lies in the fact that different strains offer distinct health benefits, such as improved gut health, enhanced immunity, better digestion, or supporting male fertility.

We determine if the probiotic cultures are paired with a prebiotic or other food source that nourishes the bacteria during digestion. This can enhance the survival rate of probiotics as they navigate through the digestive system, ensuring they reach the intestines effectively.

This examines whether the probiotic cultures in the product are alive and viable at the time of consumption, which are necessary for the probiotics to exert their beneficial effects in the gut. The effectiveness of the product often depends on the survival of these cultures through processing and storage.

CFUs represent the number of live microorganisms, typically bacteria, present in a probiotic supplement at the end of its shelf life. We like to see probiotics that provide at least 20 billion or more CFUs, though these are the ranges we consider:

The form is important because it can affect how easily the product is consumed, absorbed, and stored. Different forms may also have varying shelf lives and convenience factors for the user.

We evaluate:

Probiotic supplements are most commonly used by individuals who have digestive issues, weakened immune systems, or those that need to repopulate their gut microbiota. If you experience common digestive issues like bloating, gas, or constipation, a probiotic supplement may be beneficial in reducing or eliminating these symptoms. ( 23 )

Probiotics can also help boost the immune system by promoting the growth of good bacteria in the gut which can help fight off harmful pathogens. ( 24 ) Anyone who has recently used antibiotics may also benefit from a probiotic supplement because the antibiotics can kill beneficial bacteria in addition to the harmful ones. Probiotic supplements can help restore the balance of good bacteria in the gut after a course of antibiotics. ( 25 )

Probiotics also play a key role in enhancing nutrient absorption, offering potential benefits for health conscious individuals seeking to optimize their health. These beneficial bacteria aid in the breakdown and digestion of food in the digestive tract, enhancing the absorption of essential nutrients such as vitamins, minerals, and amino acids. ( 26 ) In turn, this has the potential to lead to performance benefits for athletes and fitness enthusiasts alike, promoting improved energy metabolism and faster recovery after intense workouts. ( 27 )

In recent years, scientists have also begun to study the gut microbiome in terms of its connection to mental health. It’s suggested that probiotics, particularly those containing certain strains of Lactobacillus and Bifidobacterium , may positively influence mental well-being by regulating the gut-brain communication pathways. These probiotics have shown promise in alleviating symptoms of depression, anxiety, and stress, possibly by reducing inflammation, balancing neurotransmitter levels, and enhancing gut barrier function. ( 26 ) However, this research is ongoing and further studies are needed to fully understand the mechanism and optimize probiotic interventions.

There is some research that probiotics can help support male fertility. Though more research is needed, one review of four studies found strains of probiotics including Lactobacillus, Bifidobacterium, and Streptococcus helped protect sperm DNA from damage and improved motility (ability to move and swim), concentration, volume, and sperm count, which could make them the best probiotics for male fertility. ( 28 )

In men, a healthy prostate helps support reproduction. Additionally, prostate cancer is one of the most common cancers for men in the U.S. A small trial found that supplementing with probioitcs may help reduce inflammation in the prostate. ( 29 ) Some research suggests the best probiotics for prostate health may include L. rhamnosu s and Lactobacillus . ( 30 )

Cortisol is a stress hormone, and when stress levels are high, it can cause other bodily functions—including testosterone production—to be compromised. One study found that those with elevated cortisol levels had lower levels of testosterone. ( 31 ) While probiotics aren’t necessarily going to increase testosterone, their potential link to lowering stress and anxiety (keeping cortisol levels in check), may help regulate testosterone production, among other processes in the body. ( 32 )

Choosing the best probiotic supplement involves a consideration of several factors.

Start by assessing your specific health needs, whether it be digestive health, immune support, mood regulation, etc. Next, prioritize probiotic strains that have been clinically studied and shown to benefit men’s health. It’s generally advised to select supplements with CFU counts exceeding 10 billion, which enhances the likelihood of the probiotics survival through the digestive tract. While no universal CFU count exists, higher counts increase the chances of living beneficial bacteria reaching the gut.

Additionally, you should only consider purchasing probiotic supplements from reputable brands. Look for supplements that are manufactured in FDA regulated cGMP facilities and those that are third-party tested for purity and safety. Some probiotics may also contain additional ingredients, like prebiotic fiber or vitamins that complement probiotic activity. These supplements can contribute to a more holistic approach to gut health, providing users with a broader spectrum of potential benefits.

Lastly, we advise reading customer reviews to evaluate the supplement’s effectiveness for individuals with similar needs as your own. Additionally, many reviews provide valuable insights into the company’s customer service, which can be important if you have specific questions about the supplement or require assistance with your order.

When starting a probiotic supplement, some potential side effects to be aware of include digestive issues such as gas, bloating, or a mild upset stomach. These effects are typically temporary and tend to resolve quickly as the body adjusts to the new bacteria.

In rare instances, individuals may experience an allergic reaction to a specific strain of probiotics. ( 33 ) However, allergic reactions are very uncommon.

While probiotic supplements are generally considered safe for most people, there are certain individuals who shouldn’t use these supplements without at least consulting with a healthcare professional first. If you have certain medical conditions like IBS, you’re undergoing medical procedures like surgery or chemotherapy, or you’re pregnant or breastfeeding, then you should definitely speak with your primary healthcare provider before starting the use of a probiotic and prebiotic supplement.

There is no one-size-fits-all approach to choosing the best probiotics, as individual needs can vary. However, probiotics that include a blend of multiple strains are typically recommended because they may provide broader benefits by supporting various aspects of gut health. Additionally, selecting probiotics with at least 10 billion CFUs is advisable to ensure a sufficient amount of viable bacteria pass through the digestive tract and reach the gut.

A man may benefit from taking probiotics, as they can enhance digestive health, immune function, and nutrient absorption. If you’re considering probiotics, try using one for at least 30 days to assess its effects. If you notice any benefits, you can continue as needed. If not, your gut microbiota may already be well-balanced and a probiotic might not be necessary.

In addition to supplements, probiotics are commonly found in a variety of cultured dairy products and fermented foods ( 34 ) Natural sources of probiotics include yogurt, kefir, sauerkraut, kimchi, and kombucha. As a nutrition coach, I would generally advise my clients to integrate whole food sources of probiotics before adding a supplement to their routine.

While probiotics offer a variety of health benefits, there’s a lack of evidence to support a direct link between probiotic use and improvements in erectile dysfunction (ED). However, ED often reflects a man’s overall health and well-being, potentially indicating issues with gut and vascular health. If you are experiencing ED, we advise seeking guidance from a healthcare professional who can offer personalized insights and steer you in the right direction concerning your condition.

Currently, there’s not enough research to determine which probiotic is good for testosterone or if probiotics increase testosterone. One small study saw improvements in testosterone in a group of men taking a probiotic and prebiotic formula containing Lactobacillus paracasei , arabinogalactan, oligo-fructosaccharides, and l -glutamine 500. ( 35 ) Though promising, more research is needed.

Follow the instructions on your probiotic supplement to find out the best time of day to take it. If the instructions are unclear, take the supplement at a time that works for you.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.

Robert Wildman, Ph.D., RD, LD, CISSN, FISSN

“Dr. Rob” is a globally renowned exercise, fitness, and nutrition expert who speaks around the world on exercise and sport nutrition, and continues to work with professional and elite athletes to achieve their highest level of performance as well as health and fitness. Rob received his Ph.D. from The Ohio State University, earned his MS from Florida State University, and earned his BS from the University of Pittsburgh. He is also a registered and licensed dietitian.

Victoria Burgess, Ph.D., CSCS, CISSN

Victoria uses her extensive nutrition and performance knowledge every day. She has a Ph.D. in Health and Human Performance from Concordia University Chicago and holds her NSCA CSCS and Certified Sports Nutritionist (CISSN). She’s an adjunct professor in the Human Performance and Nutrition department at Concordia University Chicago and Parker University, where she teaches undergraduate, graduate, and doctoral-level courses. She also sits on the advisory board for both the International Society of Sports Nutrition and the National Advisory Council of the First Responder Institute.

Joana Neziri, M.S., NASM CPT

Joana is a writer, editor, and content strategist focusing on nutrition, fitness, and all things health. After earning a master’s degree in business from the University of North Florida, she began a career in research and digital marketing.

Lily Moe

Lily is a Brooklyn-based writer and editor with over seven years of experience in health media. As a former Fitness Coach, Lily’s editorial prowess has largely focused on fitness, nutrition, and weight management. She has also spent a fair share of time in testing labs, analyzing everything from protein powders to yoga mats. Her work has appeared in Verywell Fit, Verywell Mind, Health, and more.

Kelly Uhler

Kelly has a multifaceted background in elder care, health care, and copywriting. She has worked for organizations such as A Place For Mom and Homecare.com, which gave her the opportunity to work closely with families, providing reliable information to help them make informed decisions about their loved one’s health, safety, and quality of life.

Fortune Recommends Fitness and Nutrition Writer

Pete Nastasi is a NASM-certified sports nutrition coach, personal trainer, and the owner of N2 Nutrition and Performance. Pete helps individual clients achieve their sports performance and weight-loss goals through a personalized approach centered around diet optimization, easy-to-follow workout routines, and healthy lifestyle habits.